Publications Articles, white papers and technical notes

16 results

• White paper · October 8, 2026

  Analytical Performance of the Spark UHPLC System

  Your handbook for tackling common issues and maintaining productivity.

  

• White paper · June 5, 2026

  Performance Comparison of the Spark UHPLC System Using Clinical Samples

  Liquid chromatography platforms play a critical role in clinical laboratories, where analytical robustness, peak integrity, and quantitative accuracy directly influence diagnostic decision…

  

• White paper · April 24, 2026

  Clinical Performance of the Spark UHPLC system

  Liquid chromatography plays a central role in clinical laboratories, where analytical precision and reproducibility directly influence diagnostic reliability. In this study, an…

  

• Technical note · April 20, 2026

  Automation Sample Preparation

  Automation plays a key role in modern analytical laboratories by increasing efficiency and ensuring consistent results. The Nexas Autosampler supports this need…

  

• White paper · September 15, 2025

  (U)HPLC Troubleshooting guide

  Your handbook for tackling common issues and maintaining productivity.

  

• White paper · February 18, 2025

  Dispersion in U(HPLC) flow paths

  This white paper explores how dispersion occurs due to laminar flow and how it affects peak broadening, leading to lower detection limits.

  

• Technical note · October 4, 2024

  Python integration on Linux for Spark Devices

  In this technical note, we illustrate a significant achievement: the seamless integration of the Spark Holland instrument control library (ICI) into a…

  

• White paper · September 17, 2024

  Biocompatibility in (U)HPLC Technology

  This white paper provides insight into biocompatibility based on various analytical experiments to show the importance of using the right material for…

  

• White paper · February 15, 2024

  The comparison of LC autosampler injection designs

  This white paper provides insight in the comparison of the Fixed Loop and Split Loop injection designs and helps to make a…

  

• Article · February 15, 2023

  Pump technology for (U)HPLC systems

  Choosing a pump for your (U)HPLC system depends foremost on application requirements like flow accuracy and pressure pulsation, but also on flexibility,…

  

• Article · January 4, 2023

  Sample automation for biosensor platforms

  The implementation of an automated sample preparation system for biosensor-based research permits the maximum possible efficiency resulting in the highest sample throughput,…

  

• Article · December 23, 2022

  SPH1299™ V2 and SPH1299Q™ V2

  Spark Holland has renewed her SPH1299™ and SPH1299Q™ UHPLC pumps, that were specially developed for LC-MS applications. The upgrades, which mainly concerns…